Microfluidic device for monodisperse droplets production

The invention describes geometry of the microfluidic device for production of monodisperse micrometer-sized emulsions. Presented device splits a sample into a library of monodisperse droplets of one liquid in another, immiscible liquid. Device
produces aqueous droplets in fluorinated oil containing surfactant, 30-100 nL in volume, coefficient of variation<5%. Other droplets can be produced using microfluidic devices based on proposed invention.

Inventors

Adam Opalski, Karol Makuch, Yu-Kai Lai, Piotr Garstecki

Advantages / Innovative aspects

Presented invention outperforms solutions found in literature as it offers:

• higher throughput of droplet production
• wider flowrate rate range for which the produced droplets are still monodisperse

Use

• encapsulation of biologically active ingredients
• monodisperse gel particles production
• production of nanoparticles
• culturing microorganisms in droplet
• in vitro drug screening

State of the progress
stage of research stage of development stage of prototype

Intellectual property rights
Patent application in Poland